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Isotonic Hydra-Serum

Isotonic Hydra-Serum

Intense Bio-Mimetic Hydrating Serum

Regular price £64.00
Regular price Sale price £64.00
 | 30ml
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With Hyaluronic Acid, Electrolytes, Amino Acids, Probiotics, Ceramides & 26 more Actives. 

A technical take on skin hydration, this hydrating serum not only infuses instant and long-term cellular hydration to quench thirsty skin but bio-hacks the skin to produce and regulate its own hydration. 

In addition to boosting cellular hydration and plumping to quench thirsty skin, this serum also offers anti-inflammatories to calm, replenishes vital nutrients and moisture reserves to prevent dehydration and contains ceramides to strengthen the skin’s barrier function.

Clinically-proven to increase skin hydration by up to 34% after 1 hour and 30% after 4 weeks*. 

Best for

All skin types, tones and ages, particularly dry or dehydrated.

Key benefits

  • Bio-hacks our skin cells to boost and support its own cellular Hyaluronic acid (HA)
    production rather than just supplying HA as an ingredient.
  • OSKIA’s own Biomimetic Hydra Complex is comprised of 16 synergistic actives and
    amino acids that work towards a three-pronged approach to boosting hydration:
    - Provide the building blocks to produce HA.
    - Prevent HA degradation by anti-hyaluronidase activity.
    - Stimulate HA synthesis.
  • Infuses instant hydration.
  • Re-mineralizes.
  • Strengthens the skin’s mantle & Lipid Barrier and NMF to reduce TEWL.
  • Strengthens skin mirco-flora.
  • Calms and prevents hyper-reactivity.

Key actives

Our own Biomimetic Hydra Complex (comprising 16 synergistic actives and amino acids) provides the building blocks for Hyaluronic Acid manufacture, reduces the natural hyaluronic acid destruction
caused by enzymes, and supports cellular Hyaluronic Acid synthesis for long term comfort.

Hyaluronic & Polyglutamic Acids, plus Glycerin plump and provide instant hydration to
quench thirsty skin.

Electrolytes recharge, balance and infuse water
into the skin. We have used electrolytes to ensure the balance of water within the skin cells is correct
and optimal. The minerals calcium, potassium and magnesium are linked with the PCA (pyrrolidone carboxylic acid). This naturally-occurring process plays a vital role in the pathways and balance of cellular hydration, but also helps transport key nutrients and chemicals such as ceramides.

Encapsulated Glacier Water cools and provides 24hr hydration.

Niacinamide supports the skin’s own ceramide
production to strengthen skin’s mantle and stimulates production of collagen
and fibroblasts to benefit structure and suppleness. Also balances skin tone.

Pro-Vitamin B5 stimulates cellular proliferation and
helps tissue repair. Protects skin against sunburn and aids hydration. Offers long lasting moisturisation and soothes irritated skin. It helps to improve the skin's barrier function and promotes healing.

PentaPeptide P5, Bisabolol, MSM & Horse Chestnut work in synergy to significantly calm.

Oat Ceramides – repair the lipid barrier to prevent
water loss, soothe and calm.

Awards & press

Hip & Healthy Beauty Awards 2024 - Best for Dry/Dehydrated Skin - Gold

Beauty Bible Awards 2022 - Serum Miracle Treatment - Silver

Global Makeup Awards 2021 - Best Serum (Gold)

Beauty Shortlist Awards 2021 - Best Skincare Product Innovation

Smell and feel

An extremely lightweight serum that sinks in quickly. Smells beautifully of lavender water. 

How to use

Shake before use. Apply after cleansing, morning and evening, or when skin is in need of extra hydration and comfort. Ideal post-treatment.

CAUTION: Avoid direct eye contact. If contact occurs rinse with water. Do not use on broken skin.


Lavandula Angustifolia Flower Water, Aqua (Water), Glycerin, Dimethyl Sulphone (MSM), Niacinamide (Vitamin B3), Panthenol (Provitamin B5), Acetyl Glucosamine, Leuconostoc/Radish Root Ferment Filtrate, Gluconolactone, Sodium Hyaluronate, Avena Sativa (Oat) Kernel Extract (Oat Ceramides), Calcium Ketogluconate, Betaine, Sodium Gluconate, Sodium Chloride (Himalayan Salt), Sodium PCA, Bisabolol, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Butyrospermum Parkii (Shea) Butter, Potassium Chloride, Pentapeptide-59, Polyglutamic Acid, PCA, Sodium Lactate, Serine, Alanine, Glycine, Glutamic Acid, Lysine HCL, Threonine, Arginine, Proline, Inulin Carbamate, Sclerotium Gum, Hydrogenated Lecithin, Pullulan, Silica, Maltodextrin, Citric Acid, Sodium Benzoate, Xanthan Gum, Lecithin, Sodium Hydroxide, Ethylhexylglycerin, Potassium Sorbate, Alcohol, Phenethyl Alcohol.

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Intentional Nutrients

  • Betaine

    A key amino acid, and known for its role in aiding digestion and supporting liver function. Topically, Betaine is a wonderful moisturizer, hydrator and soothing nutrient. It is also known to reinforce the skin's natural barrier function, helping to prevent water loss and protect against environmental stressors.

  • Bisabolol


    A natural compound derived from chamomile plants, renowned for its soothing and calming properties. Reduces skin irritation, redness, and inflammation making it suitable for sensitive and reactive skin. Also supports the skin's natural healing processes, making it effective in post-treatment or post-sun exposure skincare.

  • Glutamic Acid

    Glutamic Acid

    An amino acid that promotes hydration, supports the skin's natural moisture barrier, and enhances overall skin texture. It’s a component of the skin's natural moisturising factors and helps bind water to the skin, improving hydration and maintaining a smooth appearance. Contributes to a healthy moisture balance, crucial for preventing dryness and maintaining the skin's suppleness.

  • Horse Chestnut

    Horse Chestnut

    Extracted from a very British native tree, Horse Chestnut extract provides fantastic anti-inflammatory and cell protective benefits. Its main compound is escin, which helps strengthen capillary walls, promotes cell renewal and micro-circulation.

  • Hyaluronic Acid

    Used for its exceptional ability to retain moisture, holding up to 1,000 times its weight in water, which keeps the skin well-hydrated and plump. Reduces appearance of fine lines and wrinkles and promotes a smoother, more youthful complexion.

  • MSM

    Our founding mineral and the most bio-available form of sulphur, it is used in over 140 components in the body, including collagen, keratin, glutathione production and is a wonderful anti-inflammatory. Proven reduction of fine lines, helps conditions from acne and eczema to leaky gut syndrome, damaged joints, arthritis, osteoporosis and psoriasis.

  • Vitamin B3 (Niacinamide)

    Improves skin hydration, elasticity, barrier function and skin tone. Improves skin health by reducing inflammation, minimizing pore size and addressing issues like acne and hyperpigmentation. Reduces water loss by 24% in 4 weeks, boosts fatty acid and ceramides by 67% and 34% respectively; stimulates new fibroblasts by 20% and collagen secretion by 54%; inhibits pigmentation by 68%.


    Our bespoke blend of healthy-boosting amino acids helps support barrier function for super smooth, hydrated and healthy skin. It contains Alanine, Arginine, Betaine, Glycine, Lysine, Proline, Serine & Threonine.

  • OSKIA Biomimetic Hydration Complex

    Our own Biomimetic Hydration Complex is comprised of 16 synergistic actives and amino acids that provide the building blocks for Hyaluronic Acid manufacture, reduce the natural hyaluronic acid destruction by enzymes and support cellular Hyaluronic Acid synthesis for long term comfort.

  • OSKIA MSM Regen Complex

    Our Unique MSM Regen Complex is an exclusive blend of cellular nutrients that help support the skin's natural cellular processes to boost skin health.

  • Pentapeptide 59

    A biomimetic (copy of a natural compound) peptide that is based on a sea anemone protein which instantly calms sensitive skin and reduces irritation and itching. It works by inhibiting the pain receptor TRPV1.

  • Polyglutamic Acid

    Polyglutamic Acid

    A naturally occurring biopolymer peptide (a chain of glutamic amino acids) derived from fermented soybeans. It has exceptional water-binding properties holding 5,000 times its weight in water, better than Hyaluronic Acid (HA), making it a potent moisturising ingredient. However, unlike HA, PGA also has antioxidant properties, inhibits the production of melanin and potentially prevents hyaluronidase, which is the enzyme that breaks down the natural hyaluronic acid in the skin. Overall it strengthens the barrier function, improves texture, boosts skin hydration and plumps.

  • Acetyl Glucosamine

    Boosts the skin's own production of Hyaluronic Acid. A skin-conditioning ingredient derived from glucose, commonly used for its ability to promote hydration, exfoliation and even skin tone. Supports the skin's natural barrier function, enhances moisture retention and reduces the appearance of dark spots and hyperpigmentation.

  • Alanine

    One of the amino-acids used by OSKIA with wonderful calming properties to sooth irritated skin.

  • Arginine

    An amino acids that helps improve skin hydration by enhancing the skin's natural moisture-retaining abilities. It can also support the skin's natural repair processes and improve overall skin health.

  • Calcium

    Known to support skin membrane strength and aid cellular functions as well as regulate the passage of nutrients in and out of skin cell walls. This nutrient regulates sebum production to maintain skin hydration.

  • Gluconolactone


    Stimulates the production of Hyaluronic acid. Also a PHA (poly-hydroxy acids) often used instead of an AHA as an effective chemical exfoliator. The significant difference between them and AHAs is that gluconolactone has a larger molecular structure, which limits their ability to penetrate into the skin (6% reduction in skin penetration in comparison to glycolic acid), resulting in less irritating side-effects.

  • Glycerin


    A humectant used in moisturisers that absorbs water from the air, helping the skin retain water. It is a sweet, syrupy alcohol that is produced from water and fats extracted from vegetable oils. It has been used in cosmetics for hundreds of years as a solvent, plasticizer, humectant, emollient and lubricant.

  • Glycine


    An amino acid involved in collagen production, essential for wound healing and maintaining skin's elasticity. Including glycine in skincare products can support the skin's ability to repair itself. Also has anti-inflammatory properties that can help soothe and calm irritated skin, potentially reducing redness and discomfort.

  • Lavender Flower Oil

    Credited for its anti-inflammatory, antiseptic, antibacterial, soothing, healing, stimulating, antispasmodic and balancing properties. Also said to clean wounds, regulate skin functions and stimulate cellular growth and regeneration. It can produce excellent results when used in treatments for acne, burns, dermatitis, eczema and psoriasis.

  • Lysine

    A key amino acid that plays a role in collagen synthesis, which is crucial for maintaining skin's elasticity and firmness. Can support barrier function, important for maintaining hydration and protecting against external irritants. Also has wound healing, antiviral and antioxidant properties.

  • Oat Ceramides

    Oat Ceramides

    Support the skin’s barrier function by helping to prevent transepidermal water loss (TEWL) and dryness, therefore promoting a healthy skin microbiome. Soothing and calming, a great ingredient in formulas for sensitive and compromised skin.

  • Vitamin B5 (Panthenol)

    An excellent skin softener and conditioner providing suppleness and hydration to irritated skin or dry hair. Stimulates skin cellular proliferation and help tissue repair. It also protects the skin against sunburn and acts as a humectant, holding water within the product or attracting water from the environment.

  • Potassium

    Used to help regulate hydration levels, support cellular function, soothe the skin and promote a balanced pH. Helps calm irritation and contributes to overall skin health.

  • Proline


    A key amino acid and component in collagen production, helps maintain the skin's natural barrier function, essential for retaining moisture and protecting against environmental stressors. Its inclusion in skincare supports collagen synthesis and can also help minimise the appearance of scars by promoting proper tissue regeneration.

  • Sodium Chloride (Salt)

    Used for its natural cleansing, toning, refreshening, anti-inflammatory, astringent, antiseptic and moisture absorption properties. Also used as a stabiliser.

  • Sodium Gluconate

    Sodium Gluconate

    The salt form of Gluconic Acid produced from the sugar Glucose. It is used to improve the stability of a formula and can function as a humectant with isotonic functions, meaning it helps skin retain a balanced amount of water inside and outside the cell wall.

  • Sodium Lactate

    Sodium Lactate

    The sodium salt of Lactic Acid, which offers hydration-enhancing benefits when used in skincare. It’s part of our skin’s natural moisturising factor which helps to maintain skin’s hydration. It absorbs moisture from its environment and improves water retention.

  • Sodium PCA (Pyrollidone Carboxylic Acid)

    Occurs naturally in human skin derived from amino acids and is responsible for binding moisture to the cells. It is highly water-absorbent, holding several times its weight in water, which makes it an excellent humectant.

  • Threonine


    An amino acid that Contributes to skin health through its involvement in protein synthesis and overall cellular function. Its properties make it an effective ingredient in skincare products for supporting skin barrier function, moisture retention and overall skin vitality.

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  • Skin Hydration
    Boosts skin hydration (in dry, combination and oily skin) by up to 34% an hour after treatment, and up to 30% after 4 weeks. Dry Skin types saw the biggest increase in hydration, on average, by 27% after one hour and 23% after 4 weeks.
  • Plumping fine lines & wrinkles
    Reduction of shallow wrinkle size by an average 11% after 4 weeks of using the product.
    Reduction of medium wrinkle size by an average 12% after 4 weeks of using the product.


  • 100% - felt the product noticeably increased the hydration of their skin after first application.
  • 100% of subjects felt their skin was noticeably more hydrated after 4 weeks of continuous use.
  • 100% felt skin was softer.
  • 100% felt their skin appeared firmer.
  • 100 % believed their skin felt more comfortable.
  • 100% of subjects agreed that the product made their skin more moisturized.

*(Independent Clinical Study 2020 on 40 subjects (mixed ethnicity, skin type and tone with 25% Fitzpatrick 4-6), in accordance with Regulation of the European Parliament and Council Regulation (EC) No 1223/2009 of 30 November 2009 and (EC) No 655/2013 of 10 July 2013 on cosmetics)

Isotonic Hydra Serum with Lavender


What does Isotonic mean?

‘Isotonic’ means that the osmotic pressure of a ​solution inside and outside the cell is equal, that ​hydration inside and outside the cell is balanced. ​This is vital to prevent cell damage. This equal ​pressure also means that active ingredients and ​molecules are able to pass through (by osmosis) ​easily without causing harm. Too much hydration ​inside the cell (Hypotonic) will cause the cells to ​swell; too little inside the cell will cause it to ​shrink. Both lead to cellular damage. The use of ​electrolytes ensure that this solution is isotonic.

What is Bio-Hacking?

We have always worked to improve the skin’s cellular functions and processes and have always used ingredients that make the skin work more efficiently. In terms of hydration, we have looked at the chemical reactions and processes in the skin’s own synthesis of its cellular Hyaluronic Acid (HA), so rather than just providing HA in this formula we have produced our own complex called Biomimetic Hydra Complex that uses a blend of 16 actives that work synergistically to support and boost hyaluronic acid synthesis as well providing the building blocks of Hyaluronic Acid itself. We see this is a much more longterm approach to improving skin health as well as providing an immediate thirst quenching and calming effect.

Who is this product recommended for?

All skin types and ages, particularly skin that is thirsty and stressed. Also great for soothing red or hyper-reactive skin.

Is this product suitable for vegans?

Yes, this product is suitable for vegans.

Are there any tips for getting the most out of this product?

Apply 2-3 drops onto clean skin in the AM and PM or whenever extra hydration is needed.

Does this product contain parabens?

This product is FREE FROM any artificial chemicals, fragrances, preservative, colorants, petrochemicals, phthalates, DEA, TEA, sulphates or parabens.

Is this product gluten-free?

This product is free from gluten and all traces of gluten.

Can this product be used during pregnancy?

The entire OSKIA range is suitable to use during pregnancy apart from our Super-R, MSM Bio-Plus, Lactoferrin+ & Vitamin E Bath Oil. OSKIA is a natural skincare range and we use a very small quantity of organic essential oils in our products to give them a very light but lovely fragrance. As the organic essential oils are in very small quantities, they are perfectly safe to use during this very special time. For your peace of mind, if thinking of trying any of our supplements, please do consult your General Practitioner first.

Once I open this product how long can I use it for?

This product can be used for up to 9 months after initial use.